KMID : 0043320060290060476
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Archives of Pharmacal Research 2006 Volume.29 No. 6 p.476 ~ p.478
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A Convergent Synthetic Study of Biologically Active Benzofuran Derivatives
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Hu Kun
Jeong Jin-Hyun
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Abstract
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In order to construct a benzofuran library, we developed a model study of benzbromarone. Synthesis has been achieved in 53% overall yield, starting from phenol via the key intermediate 2-ethylbenzofuran which was afforded by intramolecular Wittig reaction.
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KEYWORD
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Benzbromarone, Benzofuran library, 2-Ethylbenzofuran, Intramolecular Wittig reaction
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